{"id":2146,"date":"2024-01-24T12:30:17","date_gmt":"2024-01-24T11:30:17","guid":{"rendered":"https:\/\/tafalgie.vincent-valdivieso.fr\/pipeline\/"},"modified":"2025-09-11T11:56:28","modified_gmt":"2025-09-11T09:56:28","slug":"pipeline","status":"publish","type":"page","link":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/","title":{"rendered":"Pipeline"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull hero-header\" style=\"min-height:80vh;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" class=\"wp-block-cover__image-background wp-image-4281 size-large\" alt=\"\" src=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-1024x683.jpeg\" data-object-fit=\"cover\" srcset=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-1024x683.jpeg 1024w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-300x200.jpeg 300w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-768x512.jpeg 768w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-50x33.jpeg 50w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-1600x1067.jpeg 1600w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-1536x1025.jpeg 1536w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-2048x1366.jpeg 2048w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/hero-bg-pipeline-700x467.jpeg 700w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-100 has-background-dim wp-block-cover__gradient-background has-background-gradient\" style=\"background:linear-gradient(135deg,rgba(23,44,85,0.7) 0%,rgba(13,54,144,0.7) 100%)\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div class=\"wp-block-group alignwide px-content is-layout-flow wp-block-group-is-layout-flow\" style=\"margin-top:0px\">\n<h1 class=\"wp-block-heading has-text-align-center fade-in-text has-white-color has-text-color has-link-color wp-elements-1\" style=\"font-style:normal;font-weight:700\">Un portefeuille propri\u00e9taire<br>de d\u00e9riv\u00e9s peptidiques<\/h1>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group alignfull is-layout-flow wp-container-core-group-is-layout-376a858d wp-block-group-is-layout-flow\" id=\"portefeuille-d\u00e9riv\u00e9s-peptidiques\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--70)\">\n<div class=\"wp-block-columns alignwide px-content is-layout-flex wp-container-core-columns-is-layout-946c1612 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-308ad20a wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-container-core-column-is-layout-c91f9c55 wp-block-column-is-layout-flow\" style=\"padding-right:0;flex-basis:100%\">\n<h2 class=\"wp-block-heading text-gradient from-dark-to-light_blue deco_after deco_line-orange\" style=\"margin-bottom:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--40);font-size:2rem;font-style:normal;font-weight:600\">De multiples indications et voies d\u2019administrations<\/h2>\n\n\n\n<section class=\"wp-block-group alignwide px-content has-background is-layout-flow wp-block-group-is-layout-flow\" style=\"border-top-left-radius:24px;border-bottom-right-radius:24px;background-color:#f4f5f5;padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50)\"><div class=\"hidden\"><style>#sp-ea-1242 .spcollapsing { height: 0; overflow: hidden; transition-property: height;transition-duration: 300ms;}#sp-ea-1242.sp-easy-accordion>.sp-ea-single {margin-bottom: 10px; border: 1px solid #e2e2e2; }#sp-ea-1242.sp-easy-accordion>.sp-ea-single>.ea-header a {color: #444;}#sp-ea-1242.sp-easy-accordion>.sp-ea-single>.sp-collapse>.ea-body {background: #fff; color: #444;}#sp-ea-1242.sp-easy-accordion>.sp-ea-single {background: #eee;}#sp-ea-1242.sp-easy-accordion>.sp-ea-single>.ea-header a .ea-expand-icon { float: left; color: #444;font-size: 16px;}.ea-body {\r\n  display: none;\r\n}\r\n.sp-easy-accordion .sp-ea-single {\r\n\tpointer-events: none;\r\n}\r\n\/* Hide \"+\" icons *\/\r\n.ea-header a .ea-expand-icon {\r\n   display: none;\r\n}<\/style><div id=\"sp_easy_accordion-1707480505\">\n<div id=\"sp-ea-1242\" class=\"sp-ea-one sp-easy-accordion\" data-ea-active=\"ea-click\" data-ea-mode=\"vertical\" data-preloader=\"\" data-scroll-active-item=\"\" data-offset-to-scroll=\"0\">\n\n<!-- Start accordion card div. -->\n<div class=\"ea-card  sp-ea-single\">\n\t<!-- Start accordion header. -->\n\t<h3 class=\"ea-header\">\n\t\t<!-- Add anchor tag for header. -->\n\t\t<a class=\"collapsed\" id=\"ea-header-12420\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12420\" aria-controls=\"collapse12420\" href=\"#\"  aria-expanded=\"false\" tabindex=\"0\">\n\t\t<i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i>  \t \t\t Research   \t\t  Preclinical  \t\t  Phase 1   \t\t Phase 2  \t   Lead 1 : post-operative \t\t<\/a> <!-- Close anchor tag for header. -->\n\t<\/h3>\t<!-- Close header tag. -->\n\t<!-- Start collapsible content div. -->\n\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12420\" data-parent=\"#sp-ea-1242\" role=\"region\" aria-labelledby=\"ea-header-12420\">  <!-- Content div. -->\n\t\t<div class=\"ea-body\">\n\t\tNo Content\t\t<\/div> <!-- Close content div. -->\n\t<\/div> <!-- Close collapse div. -->\n<\/div> <!-- Close card div. -->\n<!-- Start accordion card div. -->\n<div class=\"ea-card  sp-ea-single\">\n\t<!-- Start accordion header. -->\n\t<h3 class=\"ea-header\">\n\t\t<!-- Add anchor tag for header. -->\n\t\t<a class=\"collapsed\" id=\"ea-header-12421\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12421\" aria-controls=\"collapse12421\" href=\"#\"  aria-expanded=\"false\" tabindex=\"0\">\n\t\t<i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i>  \t \t\t Research   \t\t  Preclinical  \t\t  Phase 1    \t\t Phase 2  \t   Lead 1 : rare disease \t\t<\/a> <!-- Close anchor tag for header. -->\n\t<\/h3>\t<!-- Close header tag. -->\n\t<!-- Start collapsible content div. -->\n\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12421\" data-parent=\"#sp-ea-1242\" role=\"region\" aria-labelledby=\"ea-header-12421\">  <!-- Content div. -->\n\t\t<div class=\"ea-body\">\n\t\tNo Content\t\t<\/div> <!-- Close content div. -->\n\t<\/div> <!-- Close collapse div. -->\n<\/div> <!-- Close card div. -->\n<!-- Start accordion card div. -->\n<div class=\"ea-card  sp-ea-single\">\n\t<!-- Start accordion header. -->\n\t<h3 class=\"ea-header\">\n\t\t<!-- Add anchor tag for header. -->\n\t\t<a class=\"collapsed\" id=\"ea-header-12422\" role=\"button\" data-sptoggle=\"spcollapse\" data-sptarget=\"#collapse12422\" aria-controls=\"collapse12422\" href=\"#\"  aria-expanded=\"false\" tabindex=\"0\">\n\t\t<i aria-hidden=\"true\" role=\"presentation\" class=\"ea-expand-icon eap-icon-ea-expand-plus\"><\/i>  \t \t\t Research   \t\t  Preclinical  \t\t  Phase 1   \t\t Phase 2  \t   Lead 2 : acute and chronic pain \t\t<\/a> <!-- Close anchor tag for header. -->\n\t<\/h3>\t<!-- Close header tag. -->\n\t<!-- Start collapsible content div. -->\n\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12422\" data-parent=\"#sp-ea-1242\" role=\"region\" aria-labelledby=\"ea-header-12422\">  <!-- Content div. -->\n\t\t<div class=\"ea-body\">\n\t\tNo Content\t\t<\/div> <!-- Close content div. -->\n\t<\/div> <!-- Close collapse div. -->\n<\/div> <!-- Close card div. -->\n<\/div>\n<\/div>\n<\/div>\n\n\n<div id=\"sp_easy_accordion-1707480505\">\n\t<div id=\"sp-ea-1242\" class=\"sp-ea-one sp-easy-accordion\" data-ex-icon=\"minus\" data-col-icon=\"plus\"\n\t\t data-ea-active=\"ea-click\" data-ea-mode=\"vertical\" data-preloader=\"\" data-scroll-active-item=\"\"\n\t\t data-offset-to-scroll=\"0\">\n\t\t<div class=\"ea-card  sp-ea-single\">\n\t\t\t<h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12420\" data-sptoggle=\"spcollapse\"\n\t\t\t\t\t\t\t\t\t data-sptarget=\"#collapse12420\" aria-controls=\"collapse12420\"\n\t\t\t\t\t\t\t\t\t href=\"javascript:void(0)\" aria-expanded=\"false\" tabindex=\"0\"><i\n\t\t\t\tclass=\"ea-expand-icon ea-icon-expand-plus\"><\/i>\n\t\t\t\t<div class=\"pipeline-bar_ctn\">\n\t\t\t\t\t<ul class=\"pipeline-bar_bar flex list-none ml-0 mb-0 border border-second rounded-r-full\">\n\t\t\t\t\t\t<li class=\"pipeline-bar_research mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Research<\/p> <span style=\"width:100%\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t class=\"bg-second\"><\/span>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_preclinical mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Preclinical<\/p> <span\n\t\t\t\t\t\t\tstyle=\"width:100%\" class=\"bg-second\"><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase1 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 1<\/p> <span style=\"width:100%\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tclass=\"bg-second rounded-r-full\"><\/span>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase2 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 2<\/p>  <span style=\"\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t class=\"bg-second\"><\/span><\/li>\n\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<p class=\"has-large-font-size py-4 ml-8 mb-0 text-prim\"> TT5 : post-op\u00e9ratoire <\/p><\/a><\/h3>\n\t\t\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12420\" data-parent=\"#sp-ea-1242\" role=\"region\"\n\t\t\t\t aria-labelledby=\"ea-header-12420\">\n\t\t\t\t<div class=\"ea-body\">No Content<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"ea-card  sp-ea-single\">\n\t\t\t<h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12422\" data-sptoggle=\"spcollapse\"\n\t\t\t\t\t\t\t\t\t data-sptarget=\"#collapse12422\" aria-controls=\"collapse12422\"\n\t\t\t\t\t\t\t\t\t href=\"javascript:void(0)\" aria-expanded=\"false\" tabindex=\"0\"><i\n\t\t\t\tclass=\"ea-expand-icon ea-icon-expand-plus\"><\/i>\n\t\t\t\t<div class=\"pipeline-bar_ctn\">\n\t\t\t\t\t<ul class=\"pipeline-bar_bar flex list-none ml-0 mb-0 border rounded-r-full\" style=\"border-color:#F8992E;\">\n\t\t\t\t\t\t<li class=\"pipeline-bar_research mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10;\" class=\"inline-block relative mb-0\">Research<\/p>\n\t\t\t\t\t\t\t<span style=\"width:100%; background-color:#F8992E;\" class=\"rounded-r-full\"><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_preclinical mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Preclinical<\/p> <span><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase1 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 1<\/p> <span><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase2 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 2<\/p> <span><\/span><\/li>\n\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<p class=\"has-large-font-size py-4 ml-8 mb-0 text-prim\"> TTx : douleurs chronique et aigue <\/p><\/a>\n\t\t\t<\/h3>\n\t\t\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12422\" data-parent=\"#sp-ea-1242\" role=\"region\"\n\t\t\t\t aria-labelledby=\"ea-header-12422\">\n\t\t\t\t<div class=\"ea-body\">No Content<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"ea-card  sp-ea-single\">\n\t\t\t<h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12421\" data-sptoggle=\"spcollapse\"\n\t\t\t\t\t\t\t\t\t data-sptarget=\"#collapse12421\" aria-controls=\"collapse12421\"\n\t\t\t\t\t\t\t\t\t href=\"javascript:void(0)\" aria-expanded=\"false\" tabindex=\"0\"><i\n\t\t\t\tclass=\"ea-expand-icon ea-icon-expand-plus\"><\/i>\n\t\t\t\t<div class=\"pipeline-bar_ctn\">\n\t\t\t\t\t<ul class=\"pipeline-bar_bar flex list-none ml-0 mb-0 border border-second rounded-r-full\">\n\t\t\t\t\t\t<li class=\"pipeline-bar_research mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Research<\/p> <span\n\t\t\t\t\t\t\tstyle=\"width:100%;background-color:#F8992E;\"><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_preclinical mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Preclinical<\/p> <span\n\t\t\t\t\t\t\tclass=\"rounded-r-full\" style=\"width:50%;background-color:#F8992E;\"><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase1 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 1<\/p>  <span><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase2 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 2<\/p> <span><\/span><\/li>\n\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<p class=\"has-large-font-size py-4 ml-8 mb-0 text-prim\"> TT5 : maladie rare <\/p><\/a><\/h3>\n\t\t\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12421\" data-parent=\"#sp-ea-1242\" role=\"region\"\n\t\t\t\t aria-labelledby=\"ea-header-12421\">\n\t\t\t\t<div class=\"ea-body\">No Content<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"ea-card  sp-ea-single\">\n\t\t\t<h3 class=\"ea-header\"><a class=\"collapsed\" id=\"ea-header-12420\" data-sptoggle=\"spcollapse\"\n\t\t\t\t\t\t\t\t\t data-sptarget=\"#collapse12420\" aria-controls=\"collapse12420\"\n\t\t\t\t\t\t\t\t\t href=\"javascript:void(0)\" aria-expanded=\"false\" tabindex=\"0\"><i\n\t\t\t\tclass=\"ea-expand-icon ea-icon-expand-plus\"><\/i>\n\t\t\t\t<div class=\"pipeline-bar_ctn\">\n\t\t\t\t\t<ul class=\"pipeline-bar_bar flex list-none ml-0 mb-0 border border-second rounded-r-full\">\n\t\t\t\t\t\t<li class=\"pipeline-bar_research mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Research<\/p> <span style=\"width:100%\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t class=\"bg-second\"><\/span>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_preclinical mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Preclinical<\/p> <span\n\t\t\t\t\t\t\tstyle=\"width:100%\" class=\"bg-second\"><\/span><\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase1 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 1<\/p> <span style=\"width:100%\"\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tclass=\"bg-second rounded-r-full\"><\/span>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"pipeline-bar_phase2 mt-0 mb-0 w-full text-center text-sm font-medium\"><p\n\t\t\t\t\t\t\tstyle=\"z-index:10\" class=\"inline-block relative mb-0\">Phase 2<\/p> <span><\/span><\/li>\n\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<p class=\"has-large-font-size py-4 ml-8 mb-0 text-prim\"> TT5 : march\u00e9 v\u00e9t\u00e9rinaire <\/p><\/a><\/h3>\n\t\t\t<div class=\"sp-collapse spcollapse spcollapse\" id=\"collapse12420\" data-parent=\"#sp-ea-1242\" role=\"region\"\n\t\t\t\t aria-labelledby=\"ea-header-12420\">\n\t\t\t\t<div class=\"ea-body\">No Content<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t<\/div>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div id=\"essais-precliniques-et-cliniques\" class=\"wp-block-group px-content is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading text-gradient from-dark-to-light_blue deco_after deco_line-orange\" style=\"margin-bottom:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--40);font-size:2rem;font-style:normal;font-weight:600\">Les essais pr\u00e9cliniques et cliniques<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">1. Pr\u00e9clinique&nbsp;: <\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">De nombreux tests pr\u00e9cliniques r\u00e9alis\u00e9s avec des r\u00e9sultats prometteurs.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Depuis 2020, ce sont deux compos\u00e9s, des d\u00e9riv\u00e9s peptidiques de la prot\u00e9ine TAFA4, qui ont \u00e9t\u00e9 principalement utilis\u00e9s et administr\u00e9s par plusieurs voies, notamment intraveineuse, sous-cutan\u00e9e, intrath\u00e9cale ou par voie orale, donnant la perspective de r\u00e9pondre aux besoins d\u2019un grand nombre de situations m\u00e9dicales diff\u00e9rentes et ouvrant la voie \u00e0 une adoption globale.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"margin-bottom:var(--wp--preset--spacing--50)\">Pendant la phase pr\u00e9clinique, Tafalgie Therapeutics a d\u00e9montr\u00e9 que TAFA4 et ses d\u00e9riv\u00e9s peptidiques :<\/p>\n\n\n\n<ul style=\"padding-left:var(--wp--preset--spacing--40)\" class=\"wp-block-list\">\n<li><strong>Modulent efficacement la propagation de la douleur<\/strong> post-l\u00e9sionnelle, m\u00eame pour les douleurs d\u2019intensit\u00e9 mod\u00e9r\u00e9e \u00e0 s\u00e9v\u00e8re,<\/li>\n\n\n\n<li><strong>Sans les effets secondaires actuellement associ\u00e9s \u00e0 la plupart des antalgiques,<\/strong><\/li>\n\n\n\n<li><strong>Restent efficaces m\u00eame apr\u00e8s des administrations r\u00e9p\u00e9t\u00e9es<\/strong> (sans d\u00e9veloppement d\u2019accoutumance),<\/li>\n\n\n\n<li><strong>Restent efficaces m\u00eame apr\u00e8s une administration par voie orale<\/strong>, avantage exceptionnel pour un peptide.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-default\" style=\"margin-top:var(--wp--preset--spacing--60);margin-bottom:var(--wp--preset--spacing--60)\"\/>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">2. Clinique : <\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">2025 est l\u2019ann\u00e9e de l\u2019entr\u00e9e de Tafalgie en essais cliniques chez l\u2019Homme. Il s\u2019agit d\u2019une \u00e9tape cl\u00e9 dans l\u2019histoire du d\u00e9veloppement de la soci\u00e9t\u00e9.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Les essais cliniques de Tafalgie Therapeutics ont d\u00e9but\u00e9 en 2025. Le plan de d\u00e9veloppement clinique va s\u2019\u00e9talonner ainsi :<\/p>\n\n\n\n<div class=\"wp-block-group is-horizontal is-content-justification-space-between is-layout-flex wp-container-core-group-is-layout-e6e05a5c wp-block-group-is-layout-flex\">\n<div class=\"wp-block-group w-full achievement_item is-vertical is-layout-flex wp-container-core-group-is-layout-1f96cfca wp-block-group-is-layout-flex\">\n<div class=\"wp-block-group w-full has-border-color is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-b40a0a40 wp-block-group-is-layout-flex\" style=\"border-color:#efeff1;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-group w-full relative is-layout-constrained wp-container-core-group-is-layout-df57374b wp-block-group-is-layout-constrained\" style=\"min-height:55px\">\n<svg class=\"absolute\" style=\"z-index: 20; left:50%; top: -17px; transform: translate(-50%);\"  xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"34.336\" height=\"34.336\" viewBox=\"0 0 34.336 34.336\"><path d=\"M0,0-17.168,17.168,0,34.336,17.168,17.168Z\" transform=\"translate(17.168)\" fill=\"#fff\"\/><\/svg>\n\n\n\n<div class=\"wp-block-cover alignfull is-light lg:rounded-tl-3xl lg:rounded-br-3xl\" style=\"min-height:150px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1708\" class=\"wp-block-cover__image-background wp-image-4283 size-full\" alt=\"\" src=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-scaled.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-scaled.jpg 2560w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-300x200.jpg 300w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-1024x683.jpg 1024w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-768x512.jpg 768w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-50x33.jpg 50w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-1600x1067.jpg 1600w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-1536x1025.jpg 1536w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-2048x1366.jpg 2048w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-phase1-700x467.jpg 700w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-large-font-size wp-block-paragraph\"><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group w-full wp-container-content-9cfa9a5a is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-e99540d4 wp-block-group-is-layout-flex\" style=\"border-bottom-right-radius:24px;border-top-style:none;border-top-width:0px;border-right-color:#efeff1;border-right-width:3px;border-bottom-color:#efeff1;border-bottom-width:3px;border-left-color:#efeff1;border-left-width:3px;min-height:200px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\">\n<p class=\"has-text-align-center deco_after_center deco_line-orange wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:600;text-transform:uppercase\">en cours<\/p>\n\n\n\n<p class=\"has-text-align-center mx-auto max-w-lg wp-block-paragraph\" style=\"margin-top:var(--wp--preset--spacing--60);margin-bottom:var(--wp--preset--spacing--50)\"><strong>Phase 1 :<\/strong> escalade de dose en dose unique puis en doses r\u00e9p\u00e9t\u00e9es sur des volontaires sains.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group w-full achievement_item is-vertical is-layout-flex wp-container-core-group-is-layout-1f96cfca wp-block-group-is-layout-flex\">\n<div class=\"wp-block-group w-full has-border-color is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-b40a0a40 wp-block-group-is-layout-flex\" style=\"border-color:#efeff1;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-group w-full relative is-layout-constrained wp-container-core-group-is-layout-df57374b wp-block-group-is-layout-constrained\" style=\"min-height:55px\">\n<svg class=\"absolute\" style=\"z-index: 20; left:50%; top: -17px; transform: translate(-50%);\"  xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"34.336\" height=\"34.336\" viewBox=\"0 0 34.336 34.336\"><path d=\"M0,0-17.168,17.168,0,34.336,17.168,17.168Z\" transform=\"translate(17.168)\" fill=\"#fff\"\/><\/svg>\n\n\n\n<div class=\"wp-block-cover alignfull is-light lg:rounded-tl-3xl lg:rounded-br-3xl\" style=\"min-height:150px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1707\" class=\"wp-block-cover__image-background wp-image-4286 size-full\" alt=\"\" src=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-scaled.jpeg\" data-object-fit=\"cover\" srcset=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-scaled.jpeg 2560w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-300x200.jpeg 300w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-1024x683.jpeg 1024w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-768x512.jpeg 768w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-50x33.jpeg 50w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-1600x1067.jpeg 1600w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-1536x1024.jpeg 1536w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-2048x1365.jpeg 2048w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-1-700x467.jpeg 700w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-large-font-size wp-block-paragraph\"><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group w-full wp-container-content-9cfa9a5a is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-e99540d4 wp-block-group-is-layout-flex\" style=\"border-bottom-right-radius:24px;border-top-style:none;border-top-width:0px;border-right-color:#efeff1;border-right-width:3px;border-bottom-color:#efeff1;border-bottom-width:3px;border-left-color:#efeff1;border-left-width:3px;min-height:200px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\">\n<p class=\"has-text-align-center deco_after_center deco_line-orange wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:600;text-transform:uppercase\">a venir<\/p>\n\n\n\n<p class=\"has-text-align-center mx-auto max-w-lg wp-block-paragraph\" style=\"margin-top:var(--wp--preset--spacing--60);margin-bottom:var(--wp--preset--spacing--50)\"><strong>Phase 1b\/c :<\/strong> obtenir des donn\u00e9es suppl\u00e9mentaires de toxicit\u00e9 \/ s\u00e9curit\u00e9 et des premi\u00e8res donn\u00e9es d\u2019efficacit\u00e9 sur des patients op\u00e9r\u00e9s.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group w-full achievement_item is-vertical is-layout-flex wp-container-core-group-is-layout-1f96cfca wp-block-group-is-layout-flex\">\n<div class=\"wp-block-group w-full has-border-color is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-b40a0a40 wp-block-group-is-layout-flex\" style=\"border-color:#efeff1;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-group w-full relative is-layout-constrained wp-container-core-group-is-layout-df57374b wp-block-group-is-layout-constrained\" style=\"min-height:55px\">\n<svg class=\"absolute\" style=\"z-index: 20; left:50%; top: -17px; transform: translate(-50%);\"  xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"34.336\" height=\"34.336\" viewBox=\"0 0 34.336 34.336\"><path d=\"M0,0-17.168,17.168,0,34.336,17.168,17.168Z\" transform=\"translate(17.168)\" fill=\"#fff\"\/><\/svg>\n\n\n\n<div class=\"wp-block-cover alignfull is-light lg:rounded-tl-3xl lg:rounded-br-3xl\" style=\"min-height:150px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1707\" class=\"wp-block-cover__image-background wp-image-4288 size-full\" alt=\"\" src=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-scaled.jpeg\" data-object-fit=\"cover\" srcset=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-scaled.jpeg 2560w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-300x200.jpeg 300w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-1024x683.jpeg 1024w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-768x512.jpeg 768w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-50x33.jpeg 50w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-1600x1067.jpeg 1600w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-1536x1024.jpeg 1536w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-2048x1365.jpeg 2048w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/essais-clinique-a-venir-2-700x467.jpeg 700w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-large-font-size wp-block-paragraph\"><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group w-full wp-container-content-9cfa9a5a is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-e99540d4 wp-block-group-is-layout-flex\" style=\"border-bottom-right-radius:24px;border-top-style:none;border-top-width:0px;border-right-color:#efeff1;border-right-width:3px;border-bottom-color:#efeff1;border-bottom-width:3px;border-left-color:#efeff1;border-left-width:3px;min-height:200px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\">\n<p class=\"has-text-align-center deco_after_center deco_line-orange wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:600;text-transform:uppercase\">a venir<\/p>\n\n\n\n<p class=\"has-text-align-center mx-auto max-w-lg wp-block-paragraph\" style=\"margin-top:var(--wp--preset--spacing--60);margin-bottom:var(--wp--preset--spacing--50)\"><strong>Phase 2a :<\/strong> \u00e9valuation de l\u2019efficacit\u00e9 de TT5 (en cours de s\u00e9lection) pour les indications cibles y compris dans les maladies rares\u2026<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">D\u2019autres essais cliniques suivront sur des candidats m\u00e9dicaments de 2\u00e8me et 3\u00e8me g\u00e9n\u00e9ration.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Un process de s\u00e9lection, d\u2019optimisation et de production d\u2019un 2\u00e8me et 3\u00e8me candidat m\u00e9dicament est en cours. Celui-ci deviendra un m\u00e9dicament oral polyvalent, avec des co\u00fbts de production et une stabilit\u00e9 optimis\u00e9s.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<div class=\"wp-block-group is-layout-flex wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--60)\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-2c90304e wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">3. March\u00e9 v\u00e9t\u00e9rinaire : la preuve d\u2019efficacit\u00e9 translationnelle<\/p>\n\n\n\n<p class=\"wp-block-paragraph\" style=\"margin-left:0px\">L\u2019\u00e9tude TAFADOG est un essai de preuve d\u2019efficacit\u00e9 \u00e0 un stade pr\u00e9coce men\u00e9 par un partenaire acad\u00e9mique ind\u00e9pendant, dans un contexte clinique r\u00e9el avec des chiens femelles de propri\u00e9taire ayant subi une ovariectomie (st\u00e9rilisation). L\u2019\u00e9tude TAFADOG a confirm\u00e9 les effets antalgiques et pr\u00e9ventifs de TT5 dans un nouveau mod\u00e8le animal et a montr\u00e9 son efficacit\u00e9 dans un essai randomis\u00e9 en double aveugle par rapport l\u2019opio\u00efde de r\u00e9f\u00e9rence, la m\u00e9thadone.<\/p>\n<\/div>\n\n\n\n<figure class=\"wp-block-image size-medium w-full\" style=\"margin-bottom:0\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"268\" src=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-300x268.png\" alt=\"\" class=\"wp-image-4290\" style=\"object-fit:cover\" srcset=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-300x268.png 300w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-1024x915.png 1024w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-768x686.png 768w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-50x45.png 50w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-1600x1430.png 1600w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-1536x1373.png 1536w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog-700x626.png 700w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/tafadog.png 1771w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div id=\"propriete-intellectuelle\" class=\"wp-block-group px-content is-layout-constrained wp-block-group-is-layout-constrained\">\n<h2 class=\"wp-block-heading text-gradient from-dark-to-light_blue deco_after deco_line-orange\" style=\"margin-bottom:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--40);font-size:2rem;font-style:normal;font-weight:600\">La propri\u00e9t\u00e9 intellectuelle<\/h2>\n\n\n\n<div class=\"wp-block-group is-content-justification-space-between is-layout-flex wp-container-core-group-is-layout-49496290 wp-block-group-is-layout-flex\">\n<div class=\"wp-block-group wp-container-content-958eb9dc is-vertical is-layout-flex wp-container-core-group-is-layout-2c90304e wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\" style=\"font-size:1.2rem;font-style:normal;font-weight:700\">Nous disposons de 5 familles de brevets (toutes d\u00e9pos\u00e9es) dont :<\/p>\n\n\n\n<ul style=\"margin-left:0rem;padding-left:var(--wp--preset--spacing--40)\" class=\"wp-block-list\">\n<li>1 famille de brevets sous licence exclusive,<\/li>\n\n\n\n<li>2 familles de brevets en pleine propri\u00e9t\u00e9,<\/li>\n\n\n\n<li>2 autres familles d\u00e9tenues en copropri\u00e9t\u00e9 avec AMU et le CNRS et en cours d\u2019acquisition.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Avec une protection par brevets dans plus de <strong>100 pays<\/strong>, notre portefeuille de propri\u00e9t\u00e9 intellectuelle est bien positionn\u00e9 pour soutenir la commercialisation mondiale de nos compos\u00e9s.<\/p>\n<\/div>\n\n\n\n<figure class=\"wp-block-image size-full is-resized text-center flex justify-center\"><img loading=\"lazy\" decoding=\"async\" width=\"2058\" height=\"1354\" src=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte.png\" alt=\"\" class=\"wp-image-4292\" style=\"width:400px\" srcset=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte.png 2058w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-300x197.png 300w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-1024x674.png 1024w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-768x505.png 768w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-50x33.png 50w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-1600x1053.png 1600w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-1536x1011.png 1536w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-2048x1347.png 2048w, https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2025\/07\/propriete-intellectuelle-carte-700x461.png 700w\" sizes=\"auto, (max-width: 2058px) 100vw, 2058px\" \/><\/figure>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>De multiples indications et voies d\u2019administrations Research Preclinical Phase 1 Phase 2 TT5 : post-op\u00e9ratoire No Content Research Preclinical Phase 1 Phase 2 TTx : douleurs chronique et aigue No Content Research Preclinical Phase 1 Phase 2 TT5 : maladie rare No Content Research Preclinical Phase 1 Phase 2 TT5 : march\u00e9 v\u00e9t\u00e9rinaire No Content [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1992,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-2146","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pipeline - Tafalgie Therapeutics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pipeline - Tafalgie Therapeutics\" \/>\n<meta property=\"og:description\" content=\"De multiples indications et voies d\u2019administrations Research Preclinical Phase 1 Phase 2 TT5 : post-op\u00e9ratoire No Content Research Preclinical Phase 1 Phase 2 TTx : douleurs chronique et aigue No Content Research Preclinical Phase 1 Phase 2 TT5 : maladie rare No Content Research Preclinical Phase 1 Phase 2 TT5 : march\u00e9 v\u00e9t\u00e9rinaire No Content [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/\" \/>\n<meta property=\"og:site_name\" content=\"Tafalgie Therapeutics\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-11T09:56:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1688\" \/>\n\t<meta property=\"og:image:height\" content=\"1126\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/\",\"url\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/\",\"name\":\"Pipeline - Tafalgie Therapeutics\",\"isPartOf\":{\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg\",\"datePublished\":\"2024-01-24T11:30:17+00:00\",\"dateModified\":\"2025-09-11T09:56:28+00:00\",\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/#primaryimage\",\"url\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg\",\"contentUrl\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg\",\"width\":1688,\"height\":1126},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#website\",\"url\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/\",\"name\":\"Tafalgie Therapeutics\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#organization\",\"name\":\"Tafalgie Therapeutics\",\"url\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/01\/logo-tafalgie-HD-02-1024x286-1.png\",\"contentUrl\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/01\/logo-tafalgie-HD-02-1024x286-1.png\",\"width\":1024,\"height\":286,\"caption\":\"Tafalgie Therapeutics\"},\"image\":{\"@id\":\"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Pipeline - Tafalgie Therapeutics","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/","og_locale":"fr_FR","og_type":"article","og_title":"Pipeline - Tafalgie Therapeutics","og_description":"De multiples indications et voies d\u2019administrations Research Preclinical Phase 1 Phase 2 TT5 : post-op\u00e9ratoire No Content Research Preclinical Phase 1 Phase 2 TTx : douleurs chronique et aigue No Content Research Preclinical Phase 1 Phase 2 TT5 : maladie rare No Content Research Preclinical Phase 1 Phase 2 TT5 : march\u00e9 v\u00e9t\u00e9rinaire No Content [&hellip;]","og_url":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/","og_site_name":"Tafalgie Therapeutics","article_modified_time":"2025-09-11T09:56:28+00:00","og_image":[{"width":1688,"height":1126,"url":"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Dur\u00e9e de lecture estim\u00e9e":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/","url":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/","name":"Pipeline - Tafalgie Therapeutics","isPartOf":{"@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/#primaryimage"},"image":{"@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/#primaryimage"},"thumbnailUrl":"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg","datePublished":"2024-01-24T11:30:17+00:00","dateModified":"2025-09-11T09:56:28+00:00","inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/pipeline\/#primaryimage","url":"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg","contentUrl":"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/02\/pipeline-page_header.jpg","width":1688,"height":1126},{"@type":"WebSite","@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#website","url":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/","name":"Tafalgie Therapeutics","description":"","publisher":{"@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#organization","name":"Tafalgie Therapeutics","url":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/01\/logo-tafalgie-HD-02-1024x286-1.png","contentUrl":"https:\/\/tafalgie.vincent-valdivieso.fr\/wp-content\/uploads\/2024\/01\/logo-tafalgie-HD-02-1024x286-1.png","width":1024,"height":286,"caption":"Tafalgie Therapeutics"},"image":{"@id":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/pages\/2146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/comments?post=2146"}],"version-history":[{"count":76,"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/pages\/2146\/revisions"}],"predecessor-version":[{"id":5021,"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/pages\/2146\/revisions\/5021"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/media\/1992"}],"wp:attachment":[{"href":"https:\/\/tafalgie.vincent-valdivieso.fr\/fr\/wp-json\/wp\/v2\/media?parent=2146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}